I have to say yes.Before the season ,I practice from my stand and sight in.Also make sure to use good form,bend at the waist when shooting down.
Here is a take on shooting from a stand.
When you shoot your bow on level ground, the arrow is actually pointing slightly upward on the rest. When you release the string, it archers up, crosses your line of sight and then drops back down to the target. It crosses your sight line twice.
Things are different when you shoot downward from a tree stand, however. Gravity isn't working at a 90-degree angle to your line of sight anymore. The arrow arches up across your line of sight when you release the string, but now it doesn't drop back down as far. If you are using the same bow you sighted-in on the ground, you will shoot high.
Welcome to the forum.
2011 Firecat 400
2013 PSE Drive
2012 PSE Brute X